Missouri's fascinating history extends even into transportation. The National Museum of Transportation is in Kansas City, and the historic Route 66 cuts right through the middle of southern Missouri from St. Louis to Joplin, then southwest across the US. Although it isn't the main highway used anymore, Missouri takes care to preserve its legacy. There is even a "Route 66 State Park" in a small town called Eureka. Missouri's main highway is Interstate 70. It cuts straight from St. Louis to Kansas City and on west, it's a beautiful drive that will take travelers through the two largest cities in Missouri and some towns that are so small, drivers will totally miss them.

Missouri also homes five commercial airports: St. Louis (STL), Kansas City (MCI), Columbia (COU), Joplin (JLN), and Springfield (SGF). All of which have car rentals available and much of Missouri within a couple hours of driving so getting to locations in other parts of the state is relatively easy.

The Missouri and "mighty Mississippi" rivers span much of the state's geography. The entire eastern state line is formed by the Mississippi and the Missouri river starts in St. Louis and continues northwest to Montana, making it the longest river in America. Lewis and Clark spent much of their time canoeing up the Missouri in search of a river route to the Pacific Ocean.

State laws require casinos to be near a body of water, and with so much river space casino boats are popular. Many travel up and down the rivers and others are permanently docked near some of the larger cities that sit along their banks.

An unusual feature of the Missouri river is the Katy Trail. It follows the bank from St. Louis to Boonville (about 150 miles). For Missourians especially, it's a popular walking, biking and running trail that will take journeyers through lush green river valleys and along the banks of beautiful lakes.