Skopje, Macedonia
I think the most important event in Skopje, Macedonia is when Alexander's son Perdiccas 2 (this is the year 453 - 413 BC) worked on starting a war between the Athens maritime power and Sparta which lead the Peloponnesian League and initiated the creation of an Olynthian league from the Greek colonies neighboring Macedonia on Chalcidice, for a war against Athens. I think that this is important because this was 2424 years ago were alexander's son treid to start...