Tophane-i Amire was constructed in the XV. century, on the area of Ste. Claire and Aya Photini churches which called as Metopon in the Byzantine period.TAfter the conquest of Istanbul, Sultan II. Mehmet built a cannon-ball casting factory and Tophane-i Amire became a place in which the cannon balls for Ottoman army and the navy produced. After 1850s, the building became the centre of the weaponry industry and commerce. In the 1900s, it was used as an education centre. At 1958, it is started to use as a military museum. The building has undergone various arrangements until 1992. Tophane-i Amire transferred to the Mimar Sinan University at 1992.the building has been divided into three different exhibition spaces and presents local and international art shows.